Bulletin of RSMU

ISSN Print 2500–1094 ISSN Online 2542–1204

BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)

Usanova EA, Chausova SV, Filatov OYu, Krasyuk OV, Efimov BA, Balyakin YuV

In this article there was estimated a priming effect of Staphylococcus aureus and Klebsiella pneumoniae at the polymorphonuclear leukocytes by measuring luminal- and lucigenin amplified chemiluminescence of donors' blood. It was shown that bacterial antigens of both microorganisms stimulated oxidant functions of leukocytes.

Received: 2011-12-06

Published online: 2017-01-05

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Ioutsi VA, Sokolov SA, Semivrazhskaya OO, Apenova MG, Belov NM, Kovalev SV, Shevchenko VE, Negrebetsky VV

Synthesis and investigation of the antioxidative properties of four new fullerene C60 derivatives are reported. Two new synthetic procedures of the fulleropyrrolidine derivatives preparation were developed. All structures were confirmed by means of nuclear magnetic resonance spectroscopy and infrared spectroscopy, mass-spectrometry with laser desorption/ionization and high-resolution mass-spectrometry. Antioxidative properties were investigated by determination of peroxide number using the standard procedure.

Received: 2012-05-23

Published online: 2017-01-05

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Golubeva GYu, Golubev YuYu, Melentiev AS

It was studied a comparative analysis of variability of cardiac rhythm in 105 patients with complicated and uncomplicated arterial hypertension. It was shown that in the majority of patients with stable course of arterial hypertension it was found a moderate reduction in the indices of heart rate variability, reflecting a relative increase of the tone of the sympathetic nervous system while preserving parasympathetic influences. The occurrence of hypertensive crises was associated with a significant decrease in all indices of heart rate variability, clear predominance of sympathetic activity and a sharp oppression inhibition of vagal effects on the cardiovascular system.

Received: 2012-06-29

Published online: 2017-01-05

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Yudin AL, Yumatova EA, Sologubova GF, Aliev MM

The multidetector computed tomography diagnosis results of sclerosing mesenteritis in 76 patients are presented. Typical signs of sclerosing mesenteritis are discussed and indices of diagnostic value are estimated. The main pattern ("fat ring" sign) achieves 100 % specificity and positive predictive value and 75 % sensitivity.

Received: 2012-06-15

Published online: 2017-01-05

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Schegolev AA, Mitichkin AE, Al Sabunchi OA, Valetov SA, Pavlychev AV, Klochneva EA

The aim of this study was to evaluate the efficacy of using intravenous form of proton pump inhibitors in treatment of patients with upper gastrointestinal bleeding. The study included 71 patients. 30 patients in the first group received parenteral antisecretory therapy with omeprazole and the second group of 41 patients received omeprazole in capsules. The study confirmed the effectiveness of medicamental hemostasis with the usage of intravenous proton pump inhibitors in patients of that group as a part of a combined therapy based on the method of endoscopic prevention of recurrent hemorrhage.

Received: 2012-07-13

Published online: 2017-01-05

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Solodkiy VA, Sinev YuV, Ivanova OV, Grunin IB, Kolomatskaya PB

There is reviewed the potential clinical application of confocal laser endomicroscopy in the diagnosis of the gastrointestinal tract. This is a new noninvasive technique that allows with the help of a miniature confocal endomicroscopy runtime routine endiscopic procedure in vivo in real time to obtain images of the mucous membrane of the gastrointestinal tract in high resolution (the so-called virtual biopsy).

Received: 2012-06-04

Published online: 2017-01-05

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Skoroglyadov AV, Askerko EA, Tsushko VV

The outcome of treatment of 55 patients with blocked posterior dislocation of shoulder was estimated in a period of 1–24 months (mean 14.25 ± 5.91 months). The analysis showed that the index was very low with a mean value of 1.61 ± 0.42 points. The low outcome was due to the vast anatomical injuries which brought to the functional disturbances. The experience of the recovery operations showed the difficulty in the selection of operative methods. In 21 cases plastic surgery was done which was worked out in the clinic. This allowed the recovery of the anatomical interrelations and significantly improved the function of the upper extremity. It was concluded that in 9.00 ± 0.97 months after surgery and rehabilitation treatment in patients (on index scale), the pain syndrome was slightly present or completely eliminated. There was a significant increase in active movements with satisfactory and good recovery of the shoulderjoint function.

Received: 2012-03-21

Published online: 2017-01-05

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Lazishvili GD, Blinov AB, Gordienko DI, Morozov DS, Kornaev AS, Shukyur-Zade ER, Zatikyan VR

The article deals with the peculiarities of using interlocking plates and biocomposite materials in the operative treatment of proximal and distal humerus fractures. The authors in details describe basic materials and methods, surgical technology. The data obtained demonstrate that the above method allows to achieve minimally invasive humerus reposition, stabilization and early rehabilitation.

Received: 2011-12-12

Published online: 2017-01-05

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