2012 / 06

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ORIGINAL RESEARCH

Assessment of efficacy of composite dressing manufactured from hydroalginateand silver-coated fibers in treatment of patients with atopic dermatitis

Kuzovova AV1, Efimov BA2, Kulagina EV2, Korotkiy NG1
About authors

1 Department of Oncology, Hematology and Radiotherapy, Pediatric Faculty,
Pirogov Russian National Research University, Moscow, Russia

2 Department of Microbiology and Virology, Pediatric Faculty,
Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed:
Leninskii prospekt, d. 117, Moscow, Russia, 117997; e-mail is not indicated

Received: 2012-07-13 Accepted: 2012-10-31 Published online: 2017-01-05
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The aim of the research was studying of the clinical and laboratory parameters, including the assessment of a level of skin contamination with S. aureus in 25 children with atopic dermatitis, before and after the use of composite dressings manufactured from hydroalginate and silver-coated fibers. The SCORAD index before the treatment was, on average, 34.4 ± 4.0. S. aureus was detected in 18 children (72 %) with a mean concentration of 4.3 ± 4.0 CFU/cm2. Patients' affected skin areas were covered with Silvercel dressings (Johnson & Johnson) for 7 days. A microbiological test was repeated thereafter. S. aureus was detected only in 8 patients after the treatment, the level of skin contamination with S. aureus being 2.3 ± 0.2 CFU/cm2 (p < 0.05). The treatment was well-tolerated by all children. Twenty patients (80 %) had an improvement of their skin condition. The SCORAD index after the treatment was 20.35 ± 8.5 (p <   0.05). Positive changes in clinical and laboratory parameters allows to conclude that this approach is effective and safe in treatment for atopic dermatitis aggravated by a bacterial infection.

Keywords: atopic dermatitis, S. aureus, causal treatment, alginate dressings, silver-coated fibers

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