The aim of the study was to evaluate the influence of occupational risk factors on the health status of healthcare workers in the Sverdlovsk region. Complex hygienic assessment of the working conditions of healthcare personnel revealed a number of professional risk factors: physical, chemical, biological, as well as hardness and intensity of the work, which may have an unfavorable effect on the health. To the high risk group of occupational diseases relate surgeons as well as the nursing staff of surgical and therapeutic profile.