Today, a dentist can make use of any of the multitude of methods to forecast treatment effectiveness, restoration lifetime, new caries lesions development risks. However, at the national level we see no studies dedicated to evaluation of clinical effectiveness of the majority of those methods. Having analyzed the available literature, we selected CAMBRA caries development risk assessment method and made it a goal of this study to evaluate its effectiveness while also seeking to develop the most effective treatment plan. We examined 126 young adults without concomitant somatic pathologies and divided them into treatment and control groups; treatment group was then further subdivided into 3 groups depending on the risk of caries development. All patients had their teeth and tissues of the oral cavity treated following the developed and the classic plans, accordingly. After 12 months, follow-up examinations of the treatment group revealed new caries lesions in 34 (43.5%) patients, while 40 (51.3%) were diagnosed with periodontal diseases. In the control group, we found new cavities on the teeth of 25 (52.1%) patients and periodontal pathologies in 28 (58.3%) study participants. This research shows that CAMBRA and the developed treatment plan can decrease the rate of caries development in young adults.