МНЕНИЕ
Природное редактирование РНК с заменой аденозина на инозин может участвовать в патогенезе болезней человека
1 Научно-исследовательский институт биомедицинской химии имени В. Н. Ореховича, Москва, Россия
2 Российский национальный исследовательский медицинский университет имени Н. И. Пирогова, Москва, Россия
Для корреспонденции: Анна Алексеевна Ключникова
ул. Погодинская, д. 10, стр. 8, г. Москва, 119121; moc.liamg@avokinhcuilk.a
Финансирование: работа выполнена в рамках Программы фундаментальных научных исследований государственных академий наук на 2013–2020 гг.
Вклад авторов в работу: оба автора в равной степени участвовали в написании текста статьи.
- Tan MH, Li Q, Shanmugam R, Piskol R, Kohler J, Young AN, et al. Dynamic landscape and regulation of RNA editing in mammals. Nature. 2017; (550): 249–54.
- Basilio C, Wahba AJ, Lengyel P, Speyer JF, Ochoa S. Synthetic polynucleotides and the amino acid code. V Proc Natl Acad Sci USA. 1962; (48): 613–6.
- Liscovitch-Brauer N, Alon S, Porath HT, Elstein B, Unger R, Ziv T, et al. Trade-off between Transcriptome Plasticity and Genome Evolution in Cephalopods. Cell. 2017; (169): 191–202.e11.
- Gallo A, Vukic D, Michalík D, O’Connell MA, Keegan LP. ADAR RNA editing in human disease; more to it than meets the I. Hum Genet. 2017; (136): 1265–78.
- Young PE, Kum Jew S, Buckland ME, Pamphlett R, Suter CM. Epigenetic differences between monozygotic twins discordant for amyotrophic lateral sclerosis (ALS) provide clues to disease pathogenesis. PLoS One. 2017; (12): e0182638.
- Taylor DR, Puig M, Darnell MER, Mihalik K, Feinstone SM. New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1. J Virol. 2005; (79): 6291–8.
- Suspène R, Petit V, Puyraimond-Zemmour D, Aynaud MM, Henry M, Guétard D, et al. Double-stranded RNA adenosine deaminase ADAR-1-induced hypermutated genomes among inactivated seasonal influenza and live attenuated measles virus vaccines. J Virol. 2011; (85): 2458–62.
- John L, Samuel CE. Induction of stress granules by interferon and down-regulation by the cellular RNA adenosine deaminase ADAR1. Virology. 2014; (454–455): 299–310.
- Crow YJ. Aicardi-Goutières syndrome. Handb Clin Neurol. 2013; (113): 1629–35.
- Tomczak K, Czerwińska P, Wiznerowicz M. The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge. Contemp Oncol (Poznan, Poland). 2015; (19): A68–77.
- Peng X, Xu X, Wang Y, Hawke DH, Yu S, Han L, et al. A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer. Cancer Cell. 2018; (33): 817–828.e7.
- Galeano F, Rossetti C, Tomaselli S, Cifaldi L, Lezzerini M, Pezzullo M, et al. ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis. Oncogene. 2013; (32): 998–1009.
- Chen L, Li Y, Lin CH, Chan THM, Chow RKK, Song Y, et al. Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma. Nat Med. 2013; (19): 209–16.
- Han L, Diao L, Yu S, Xu X, Li J, Zhang R, et al. The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers. Cancer Cell. 2015; (28): 515–28.
- Xu X, Wang Y, Liang H. The role of A-to-I RNA editing in cancer development. Curr Opin Genet Dev. 2018; (48): 51–6.