Here we present a rare case of inflammation in the Meckel's diverticulum with the ectopic pancreatic tissue in a 18-year-old patient. Laparoscopy converted to laparotomy was performed. The inflamed Meckel's diverticulum was found during intraoperative revision, which was the reason to perform segmental resection of the affected area of the small intestine with the construction of an enteroenteric anastomosis. Pathological examination of surgical material revealed mature exocrine tissue of the pancreas without any signs of cellular atypia, which confirmed the presence of pancreatic heterotopia in the Meckel's diverticulum. The reported case demonstrates rarity of such combination of abnormalities, highlights diagnostic difficulties at the preoperative stage, and draws attention to the need for thorough intraoperative revision of the small intestine, as well as for mandatory morphological verification to establish the final diagnosis and determine further patient management tactics.