ISSN Print 2500–1094
ISSN Online 2542–1204
Bulletin of RSMU
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
The influence of complex bacterial preparations on oxidant functions of polymorphonuclear leukocytes of donors’ blood
About authors
1 Department of General Pathology, Biomedical Faculty,
Pirogov Russian National Research Medical University, Moscow, Russia
2 Department of Faculty Surgery No. 1, Medical Faculty,
A. I. Evdokimov Moscow State Medical and Dental University, Moscow
3 Department of Microbiology and Virology, Pediatric Faculty,
Pirogov Russian National Research Medical University, Moscow, Russia
Correspondence should be addressed: Elena Usanova
ul. Ostrovityanova, d. 1, Moscow, Russia, 117997; ur.kb@anela.avonasu
Received: 2011-12-06
Accepted: 2012-09-19
Published online: 2017-01-05
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In this article there was estimated a priming effect of Staphylococcus aureus and Klebsiella pneumoniae at the polymorphonuclear leukocytes by measuring luminal- and lucigenin amplified chemiluminescence of donors' blood. It was shown that bacterial antigens of both microorganisms stimulated oxidant functions of leukocytes.
Keywords: chemiluminescence, polymorphonuclear leukocytes, priming, bacterial antigens