ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
The antioxidant activity of plants used in Tuvan ethnomedicine
About authors
1 Laboratory of Bioactive Compounds, Research Institute of Pharmacy,
I. M. Sechenov First Moscow State Medical Unversity, Moscow, Russia
2 Department of Medical Biophysics, Institute for Fundamental and Applied Biomedical Research,
Pirogov Russian National Research Medical University, Moscow, Russia
3 Department of General and Medical Biophysics, Biomedical Faculty,
Pirogov Russian National Research Medical University, Moscow, Russia
4 Department of Organization of Pharmaceutical Activity, Pharmaceutical Faculty,
Pirogov Russian National Research Medical University, Moscow, Russia
Correspondence should be addressed: Nino Chekhani
ul. Trubetskaya, d. 8, str. 2, Moscow, Russia, 119991; ur.liam@onininahehc
Received: 2012-07-09
Accepted: 2012-10-31
Published online: 2017-01-05
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In this study the antioxidant activity (AOA) of water extracts of some plants used in Tuva ethnomedicine was investigated. As a model system there was used a system in which the reaction of free radical oxidation of luminol was induced by adding 2,2'-azobis(2-amidinopropane) dihydrochloride (ABAP). The process of luminol oxidation was observed by recording its chemiluminescence. It was found that addition of water extracts from the studied plants to АВАР-luminol system resulted in the inhibition of luminol chemiluminescence and the appearance of the latent period, the duration of which was directly proportional to the amount of the added sample. Water extracts of herb meadowsweet (Filipendula ulmaria L.) had the highest AOA, and the least — the leaves of warty birch (Betula pendula Roth.) and black currant (Ribes nigrum L.). It is assumed that the AOA of water plants extracts is due to phenol and polyphenol compounds.
Keywords: chemiluminescence, plant material, water extracts, antioxidants, antioxidant activity