ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
METHOD
Gadolinium- and curcumin-loaded micelles based on α-fetoprotein functionalized amphiphilic block copolymers
About authors
1 Laboratory of Radionuclide and Beam Technologies in Experimental Oncology,N. N. Blokhin Russian Cancer Research Center, Moscow, Russia
2 Laboratory of Light Sensitization,N. M. Emanuel Institute of Biochemical Physics, RAS, Moscow, Russia
Correspondence should be addressed: Natalia V. Pozdnyakova
Kashirskoe shosse, d. 24, Moscow, Russia, 115478; ur.liam@2002optan
About paper
Funding: the study was supported by the Ministry of Education and Science of the Russian Federation (Grant Agreement no.14.607.21.0133 dated October 27, 2015, Project ID RFMEFI60715X0133).
Received: 2016-06-23
Accepted: 2016-06-27
Published online: 2017-01-05
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Fig. 2. Structure of amphiphilic triblock copolymers Pluronic F-127 and Pluronic P-123 (Sigma-Aldrich, USA), where a represents the number of hydrophilic monomers and b represents the number of hydrophobic monomers. For Pluronic F-127, the a-b-a formula is 98–67–98. For Pluronic P-123, the a-b-a formula is 20–70–20
Fig. 4. Schematic of obtaining gadolinium-containing functionalized micelles
Micelle composition
Note. P-123 — Pluronic P-123, F-127 — Pluronic F-127 (Sigma-Aldrich, USA).
