ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
Frequency of carbohydrate metabolism disorders in day-care patients with borderline fasting blood sugar levels and at least one risk factor for diabetes mellitus
About authors
1 Department of Endocrinology, Federal Clinical Centre of High Medical Technologies, Moscow Region, Novogorsk, Russia
2 Tambov Central Regional Hospital, Pokrovo Prigorodnoe Rural Settlement, Russia
3 Pirogov Russian National Research Medical University, Moscow, Russia
Correspondence should be addressed: Valentina V. Boeva
Ivanovskaya st., 3, Novogorsk, Moscow region, Russia, 141435; ur.xednay@VVaveoB
About paper
Author contribution: all authors participated in conceiving and planning the study, collected and analyzing the data. Boeva VV prepared the study for publication.
Received: 2018-08-10
Accepted: 2019-03-02
Published online: 2019-03-16
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Fig. 1. The study included 91 patients, who were then distributed into 3 groups depending on their blood sugar levels. Patients with FPG ≥ 7.0 mmol/L (measured in
two repeated tests) were diagnosed with type 2 DM and prescribed adequate treatment. Patients with FPG between 6.1 and 6.9 mmol/L underwent an oral glucose
tolerance test (OGTT). Patients with FPG between 5.6 and 6.0 mmol/L who were at risk for developing type 2 DM and metabolic syndrome also underwent OGGT.
FPG — fasting plasma glucose
Fig. 2. The overall distribution of the patients depending on the severity of carbohydrate metabolism disorders revealed by OGTT. IFG — impaired fasting glucose;
IGT — impaired glucose tolerance; OGTT — oral glucose tolerance test
Fig. 3. The distribution of the patients depending on the severity of carbohydrate metabolism disorders revealed by OGTT in the group of 35 individuals with initial FPG
between 5.6 and 6.0 mmol/L. IFG — impaired fasting glucose; IGT — impaired glucose tolerance; OGTT — oral glucose tolerance test
Fig. 4. The distribution of the patients depending on the severity of carbohydrate metabolism disorders revealed by OGTT in the group of 34 individuals with initial FPG
between 6.1 and 6.9 mmol/L. IFG — impaired fasting glucose; IGT — impaired glucose tolerance; OGTT — oral glucose tolerance test
Table 1. Clinical and demographic characteristics of patients
Note: *— differences are significant, р < 0.05; BMI — body mass index; IFG — impaired fasting glucose; IGT— impaired glucose tolerance; AMI — acute myocardial infarction; ACE — acute cerebrovascular event; WC — waist circumference; OGTT— oral glucose tolerance test; DM — diabetes mellitus; TIA — transient ischemic attack.
Table 2. The distribution of the patients depending on the severity of carbohydrate metabolism disorders (OGTT)
Note: *— differences are significant, р < 0.05; FPG — fasting plasma glucose; IFG — impaired fasting glucose; IGT— impaired glucose tolerance; OGTT— oral glucose tolerance test; DM — diabetes mellitus. In the subgroup of patients with FPG levels ranging from 5.6 to 6.0 mmol/L, there were 2.8% cases of IFG, 11.5% cases of IGT and 4.3% cases of type 2 DM (based on OGTT results). Thus, the frequency of prediabetic conditions in the subgroup was 14.4%. The frequency of IGT was significantly lower in the subgroup with FPG between 6.1 and 6.9 mmpl/L.
