2022 / 01

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DOI: 10.24075/brsmu.2022.007

ORIGINAL RESEARCH

Dynamic changes in the concentration of anti-SARS-CoV-2 antibodies within 12 months after recovery from COVID-19

Mayanskiy NA1, Brzhozovskaya EA1, Stoyanova SS1, Frolkov AV1, Lebedin YuS2
About authors

1 Pirogov Russian National Research Medical University, Moscow, Russia

2 XEMA LLC, Moscow, Russia

Correspondence should be addressed: Nikolay A. Mayanskiy
Ostrovitianova, 1, Moscow, Russia; moc.liamg@yalokin.yiksnayam

About paper

Author contribution: Mayansky NA — concept, data processing, manuscript writing; Brzhozovskaya EA — sample collection, ELISA, data processing, making illustrations; Stoyanova SS — sample collection, data processing, making illustrations; Frolkov AV — data processing, manuscript preparation; Lebedin YuS — concept, ELISA, manuscript editing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Pirogov Russian National Research Medical University (protocol № 197 dated May 21, 2020).

Received: 2022-02-01 Accepted: 2022-02-14 Published online: 2022-02-20
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Fig. Concentration of anti-RBD IgG as a function of time after the positive PCR test result for SARS-CoV-2. (А) individual values for 97 samples and (B) geometric mean titers (GMT) of anti-RBD IgG with the 95% CI, expressed in BAU/mL; dotted line in (А) at the level of 15 BAU/mL specifies the positivity threshold