CLINICAL CASE

Type 1 diabetes mellitus: features of differential diagnosis

Gantsgorn EV, Denisenko OV, Osipenko YaO, Kalmykova DA, Ivanov AV, Gerasyuta SS, Bulguryan GA, Ivanova MH, Saakyan DA
About authors

Rostov State Medical University of the Ministry of Health of the Russian Federation, Rostov-on-Don, Russia

Correspondence should be addressed: Elena V. Gantsgorn
1-ja Mayskaya, 8/10, 16, Rostov-on-Don, 344019, Russia; ur.xobni@nrogstnag

About paper

Author contribution: Gantsgorn EV — study concept, interpretation of results, manuscript editing; Denisenko OV, Osipenko YaO — literature analysis, data analysis, interpretation of results, manuscript writing; Kalmykova DA, Ivanov AV, Gerasyuta SS, Bulguryan GA, Ivanova MH, Saakyan DA — literature analysis, data analysis.

Compliance with ethical standards: the patient signed a voluntary informed consent to the publication of personal medical information in an anonymized form.

Received: 2023-05-13 Accepted: 2023-06-14 Published online: 2023-06-26
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  1. Federal'nyj Registr saxarnogo diabeta RF; 2023 [Ehlektronnyj resurs] [data obrashheniya: 11.06.2023]. Dostupno po ssylke: https://sd.diaregistry.ru/content/o-proekte.html#content. Russian.
  2. Buzzetti R, Tuomi T, Mauricio D, Pietropaolo M, Zhou Z, Pozzilli P, et al. Management of latent autoimmune diabetes in adults: a consensus statement from an international expert panel. Diabetes. 2020; 69 (10): 2037–47. PMID: 32847960; PMCID: PMC7809717.7.
  3. DiMeglio LA, Evans-Molina C, Oram RA. Type 1 diabetes. Lancet. 2018; 391 (10138): 2449–62. PMID: 29916386; PMCID: PMC6661119.
  4. Meijer JW, Smit AJ, Sonderen EV, Groothoff JW, Eisma WH, Links TP. Symptom scoring systems to diagnose distal polyneuropathy in diabetes: the diabetic neuropathy symptom score. Diabet Med. 2002; 19 (11): 962–5. PMID: 12421436.
  5. Fourlanos S, Perry C, Stein MS, Stankovich J, Harrison LC, Colman PG. A clinical screening tool identifies autoimmune diabetes in adults. Diabetes Care. 2006; 29 (5): 970–5. PMID: 16644622.
  6. Pieralice S, Pozzilli P. Latent autoimmune diabetes in adults: a review on clinical implications and management. Diabetes Metab J. 2018; 42 (6): 451–64. PMID: 30565440; PMCID: PMC6300440.
  7. Zampetti S, Capizzi M, Spoletini M, Campagna G, Leto G, Cipolloni L, et al. GADA titer-related risk for organ-specific autoimmunity in LADA subjects subdivided according to gender (NIRAD study 6). J Clin Endocrinol Metab. 2012; 97 (10): 375965. PMID: 22865904.
  8. Leslie RD, Williams R, Pozzilli P. Clinical review: Type 1 diabetes and latent autoimmune diabetes in adults: one end of the rainbow. J Clin Endocrinol Metab. 2006; 91 (5): 1654–9. PMID: 16478821.
  9. Hernandez M, Mollo A, Marsal JR, Esquerda A, Capel I, PuigDomingo M, et al. Insulin secretion in patients with latent autoimmune diabetes (LADA): half way between type 1 and type 2 diabetes: action LADA 9. BMC Endocr Disord. 2015; 15: 1. PMID: 25572256; PMCID: PMC4297398.
  10. American Diabetes Association Professional Practice Committee; 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes — 2022. Diabetes Care. 2022; 45 (Supplement 1): S17–S38.
  11. Akil AA, Yassin E, Al-Maraghi A, Aliyev E, Al-Malki K, Fakhro KA. Diagnosis and treatment of type 1 diabetes at the dawn of the personalized medicine era. J Transl Med. 2021; 19 (1): 137. PMID: 33794915; PMCID: PMC8017850.
  12. Timakova AA, Saltykov BB. Osobennosti razvitiya latentnogo diabeta vzroslyh (LADA). Arxiv patologii. 2019; 81 (4): 78–82. Russian.
  13. Hernández M, Nóvoa-Medina Y, Faner R, Palou E, Esquerda A, Castelblanco E, et al. Genetics: Is LADA just late onset type 1 diabetes? Front Endocrinol (Lausanne). 2022; 13: 916698. PMID: 36034444; PMCID: PMC9404871.
  14. Said G, Goulon-Goeau C, Slama G, Tchobroutsky G. Severe earlyonset polyneuropathy in insulin-dependent diabetes mellitus. A clinical and pathological study. N Engl J Med. 1992; 326 (19): 1257–63. PMID: 1560802.
  15. Shafi OM, Latief M. Early onset symptomatic neuropathy in a child with Type 1 Diabetes mellitus. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2017; 11 (Suppl 1): S477–S479.