2024 / 02

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DOI: 10.24075/brsmu.2024.012

ORIGINAL RESEARCH

Treatment of gonarthrosis using autologous platelet-rich plasma

Egiazaryan KA, Danilov MA, Abdusalamov RM
About authors

Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Maxim A. Danilov
Ostrovityanova, 1, Moscow, 117997, Russia; moc.liamg@volinad.dm

About paper

Author contribution: Egiazaryan KA, Danilov MA — study design development, analysis of results; Danilov MA, Abdusalamov RM — data collection, literature review, preparation administration, assessment of the results.

Compliance with ethical standards: the study was approved by the Ethics Committee of the N.I. Pirogov Russian National Research Medical University (Minutes #213 of December 13, 2021).

Received: 2024-01-30 Accepted: 2024-03-02 Published online: 2024-04-19
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Fig. 1. Initial pain intensity dynamics after over 30 minutes of rest, all groups, percentages. * — significance of differences (p < 0.05) between indicators of the control group and those registered for groups 1 and 2; * * — significance of differences (p < 0.001) between indicators of the control group and group 2
Fig. 2. Morning joint stiffness dynamics, all participants, percentages. * — significance of differences (p < 0.05) between indicators of the control group and those registered for groups 1 and 2; * * — significance of differences (p < 0.001) between indicators of the control group and groups 1 and 2
Fig. 3. Dynamics of the physical indicators of QOL, as registered with a SF-36 survey before treatment, 3 and 6 months thereafter. * — significance of differences (p < 0.05), indicator's value before and after treatment, intragroup; * * — significance of differences (p < 0.001), indicator's values, treatment group and comparison group, 3 and 6 months after treatment
Fig. 4. Dynamics of the mental indicators of QOL, as registered with a SF-36 survey before treatment, 3 and 6 months thereafter. * — significance of differences (p < 0.05) of the indicator values before and after treatment.
Fig. 5. Pain intensity, VAS registration, all patients (points). * — significance of differences (p < 0.05), indicator's value compared to control group; * * — significance of differences (p < 0.001), indicator's values, treatment group and comparison group compared
Table. Dynamics of ultrasonography indicators of the knee OA against the background of treatment, all patients
Note: * — significance of differences (p < 0.05) of the indicator values before and after treatment, intragroup.