ORIGINAL RESEARCH

Determining optimal ambient ionization mass spectrometry data pre-processing parameters in neurosurgery

About authors

1 Moscow Institute of Physics and Technology, Moscow, Russia

2 Semenov Federal Research Center for Chemical Physics of the Russian Academy of Sciences, Moscow, Russia

3 Skolkovo Institute of Science and Technology, Moscow, Russia

4 Siberian State Medical University, Tomsk, Russia

Correspondence should be addressed: Denis S. Zavorotnyuk
Institutskiy per., 9, str. 7, Dolgoprudny, Moscow Region, 141701; moc.liamg@kuyntorovaz.sined

About paper

Funding: the study was performed within the framework of the state assignment of the Ministry of Science and Higher Education of the Russian Federation (agreement № 075-03-2022-107, project № 0714-2020-0006). The study involved the use of equipment of the Semenov Federal Research Center for Chemical Physics RAS.

Author contribution: Zavorotnyuk DS — data acquisition and interpretation, software development, manuscript writing and editing; Sorokin AA — study planning, data analysis and interpretation, manuscript editing; Bormotov DS — data acquisition and interpretation, manuscript writing; Eliferov VA — financial support of the experiment; Bocharov KV — data acquisition; Pekov SI — study planning, data analysis and interpretation, manuscript draft writing and manuscript text finalization; Popov IA — project management, financial support.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Burdenko Research Institute of Neurosurgery (protocols № 40 dated 12 April 2016 and № 131 dated 17 July 2018) and conducted in accordance with the principles of the Declaration of Helsinki (2000) and its subsequent revisions. All patients submitted the informed consent to study participation and the use of biomaterial for scientific purposes.

Received: 2024-12-19 Accepted: 2024-03-03 Published online: 2024-04-27
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