ORIGINAL RESEARCH

Potentially inappropriate prescribing among critically ill children: POPI-criteria in Russia

Vlasova AV1,2,3, Kulichenko TV4, Smirnova EV2
About authors

1 Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation, Moscow, Russia

2 Morozov Children's City Clinical Hospital, Moscow, Russia

3 Research Institute of Healthcare Organization and Medical Management, Moscow, Russia

4 Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Anna V. Vlasova
4th Dobryninsky pereulok, 1/9, Moscow,119049, Russia; ur.liam@57avosalvanna

About paper

Author contribution: Vlasova AV — study concept and design, data acquisition and processing, manuscript writing and editing; Smirnova EV — statistical data processing, manuscript editing; Kulichenko TV — manuscript editing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Morozov Children's City Clinical Hospital (the research protocol dated 24.10.2019 was published on ClinicalTrials.gov, ID: NCT04141657, Unique Protocol ID: 07819001, Brief Title: Safety Analysis of Antimicrobial Pharmacotherapy in Intensive Care Unit at Pediatric Hospital Official, Title: Observational Prospective Multidirectional Study on the Safety of Antimicrobial Pharmacotherapy in Intensive Care Unit (ICU) Children Aged 0-17).

Received: 2024-02-21 Accepted: 2024-04-27 Published online: 2024-04-30
|
  1. Impicciatore P, Choonara I, Clarkson A, Provasi D, Pandolfini C, Bonati M. Incidence of adverse drug reactions in paediatric in/outpatients: a systematic review and meta‐analysis of prospective studies. Br J Clin Pharmacol. 2001; 52 (1): 77–83.
  2. Li S, Huang L, Zeng L, Yu D, Jia ZJ, Cheng G, et al. A tool for screening potentially inappropriate prescribing in Chinese children. Front Pharmacol. 2022; 13: 1019795.
  3. Zhao Z, Shen J, Shen C, Zhu B, Sun J, Yu J,et al. An investigation of pharmacovigilance and reporting of adverse drug reactions in hospitals: a cross-sectional study in China. Curr Med Res Opin. 2021; 37 (11): 2001–6.
  4. Balan S, Hassali MAA, Mak VS. Two decades of off-label prescribing in children: a literature review. World J Pediatr. 2018; 14: 528–40.
  5. Berthe-Aucejo A, Nguyen PKH, Angoulvant F, Bellettre X, Albaret P, Weil T, et al. Retrospective study of irrational prescribing in French paediatric hospital: prevalence of inappropriate prescription detected by Pediatrics: Omission of Prescription and Inappropriate prescription (POPI) in the emergency unit and in the ambulatory setting. BMJ Open. 2019; 9 (3): e019186.
  6. Prot-Labarthe S, Weil T, Angoulvant F, Boulkedid R, Alberti C, Bourdon O. POPI (Pediatrics: Omission of Prescriptions and Inappropriate prescriptions): development of a tool to identify inappropriate prescribing. PloS One. 2014; 9 (6): e101171.
  7. Barry A, Olsson S, Minzi O, Bienvenu E, Makonnen E, Kamuhabwa A, et al. Comparative assessment of the national pharmacovigilance systems in East Africa: Ethiopia, Kenya, Rwanda and Tanzania. Drug Saf. 2020; 43: 339–50.
  8. Corrick FJ. Paediatric rational prescribing: a study of paediatric rational prescribing tools and development of a novel tool for the UK. 2021.
  9. Gallagher P, Ryan C, Byrne S, Kennedy J, O Mahony D. STOPP (screening tool of older person’s prescriptions) and START (screening tool to alert doctors to right treatment). Consensus validation. Int J Clin Pharmacol Ther. 2008; 46 (2): 72.
  10. Vlasova AV. Nezhelatel'nye reakcii detej na antimikrobnye preparaty: ogranichenija metoda spontannyh soobshhenij i vozmozhnosti metoda global'nyh triggerov lekarstvenno-inducirovannyh sostojanij. Farmateka. 2023 (1–2): 18–31. Russian.
  11. Jakovlev SV, Briko NI, Sidorenko SV, Procenko DN. Programma SKAT (strategija kontrolja antimikrobnoj terapii) pri okazanii stacionarnoj medicinskoj pomoshhi: Rossijskie klinicheskie rekomendacii. M.: Pero, 2018; 156 s. Russian.
  12. Centers for Disease Control and Prevention, CDC. Available from: https://www.cdc.gov/hai/vap/vap.html.
  13. European Centre for Disease Prevention and Control, ECDC. Available from: https://www.cdc.gov/hai/vap/vap.html.