2024 / 04

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DOI: 10.24075/brsmu.2024.031

ORIGINAL RESEARCH

Assessment of blood amino acid and polyamine levels in placenta-associated pregnancy complications

Gasanbekova AP1, Frankevich NA1, Chagovets VV1, Dolgopolova EL1, Novoselova AV1, Karapetyan TE1, Mamedova GE2, Frankevich VE1,3
About authors

1 Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia

2 Peoples' Friendship University of Russia, Moscow, Russia

3 Siberian State Medical University, Tomsk, Russia

Correspondence should be addressed: Natalia A. Frankevich
Akademika Oparina, 4, Moscow, 117997, Russia; ur.xednay@avomol-ahsatan

About paper

Funding: the study was supported by the RSF grant No. 22-15-00232 “New Noninvasive Diagnostic Approaches for Optimization of Obstetric Tactics, Prediction of Perinatal Outcomes, and Prevention of Abnormal Postnatal Growth in Fetal Growth Restriction Syndrome”.

Author contribution: Gasanbekova AP — collection and preparation of biological media, manuscript writing; Frankevich NA — clinical data analysis, systematic analysis, manuscript writing; Chagovets VV — metabolomics analysis by mass spectrometry, statistical analysis of the data acquired, manuscript editing; Dolgopolova EL — clinical data analysis, statistical data processing; Novoselova AV — metabolomics analysis by mass spectrometry, mass spectrometry data processing; Karapetyan TE — clinical data analysis, manuscript editing; Mamedova GE — collection and preparation of biological media; Frankevich VE — preparation and control, manuscript editing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology (protocol No. 11 dated 11 November 2021), the study met the requirements of the Declaration of Helsinki, International Conference on Harmonization (ICF), Good Clinical Practice (GCP), and Federal Law “On the Basics of Protecting Citizens' Health in the Russian Federation”; the informed consent was submitted by all patients.

Received: 2024-06-21 Accepted: 2024-07-24 Published online: 2024-08-15
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