Copyright: © 2025 by the authors. Licensee: Pirogov University.
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ORIGINAL RESEARCH

Intravital microscopy for assessment of anti-tumor nanotherapeutic delivery

About authors

1 National University of Science and Technology MISIS, Moscow, Russia

2 Serbsky National Medical Research Centre for Psychiatry and Narcology, Moscow, Russia

3 Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Elizaveta V. Ivanova
Leninsky Prospect, 4, str. 1, 119049, Moscow, Russia; ur.sisim.ude@4103081m

About paper

Funding: the study was supported by the Russian Science Foundation grant (project No. 21-74-20077).

Author contribution: Ivanova EV, Naumenko VA — manuscript writing, design of the figures; Garanina AS, Abakumov MA — manuscript editing.

Received: 2025-06-17 Accepted: 2025-06-29 Published online: 2025-06-30
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Fig. 1. Role of leukocytes in delivery of anti-tumor nanopharmaceuticals. А. Mechanisms underlying extravasation of magnetite nanoparticles in the tumor microvascular bed. B. Mechanisms underlying extravasation of liposomes in the tumor microvascular bed
Fig. 2. Mechanism underlying renal excretion of nanoparticles with the size above the glomerular filtration threshold