ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
Copyright: © 2025 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
ORIGINAL RESEARCH
Assessment of blood catecholamine and serotonin levels in anxiety and depressive disorders
About authors
1 Scientific Centre of Personalized Medicine, Moscow, Russia
2 Diagnostic and Treatment Center, Berezin Medical Institute, Moscow, Russia
3 Mental Health Research Center, Moscow, Russia
4 Pirogov Russian National Research Medical University, Moscow, Russia
Correspondence should be addressed: Irina V. Kichuk
Ostrovityanova, 1, Moscow, 119021, Russia; ur.liam@aniri2liam
About paper
Author contribution: Solovyova NV, Kichuk IV — study concept and design; Solovyova NV, Kochergina KV, Mitrofanov AA, Kichuk IV — material collection and processing; Chuprova NA, Kochergina KV — statistical data processing; Mitrofanov AA, Kichuk IV, Solovyova NV, Kochergina KV — manuscript writing; Mitrofanov AA, Kichuk IV, Solovyova NV, Kochergina KV, Chausova SV — editing.
Compliance with ethical standards: the study was approved by the Ethics Committee of the Joint Stock Company “Scientific Centre of Personalized Medicine” (protocol No. 33 dated 1 December 2025). The subjects’ personal data were hidden during the study. All the subjects submitted the informed consent for participation in the study.
Received: 2025-10-30
Accepted: 2025-12-08
Published online: 2025-12-19
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Table 1. Comparison of patients with clinical anxiety based on HADS-A with other patients
Note: р — asymptote (bilateral), U — Mann–Whitney U-test.
Table 2. Comparison of patients with clinical depression based on HADS-D with other patients
Note: р — asymptote (bilateral), U — Mann–Whitney U-test.
Table 3. Clinical depression prognosis (HADS-D) regression analysis results
Note: SE — standard error of the mean. Model characteristics: Х2 = 16.398, р = 0.001; –2 Log-likelihood=103.909.
Table 4. Comparison of patients with the clinical diagnoses of depression and anxiety based on biochemical indicators
Note: р — asymptote (bilateral), U — Mann–Whitney U-test.
Table 5. Comparison of patients with the clinical diagnoses of anxiety and “Other” based on biochemical indicators
Note: р — asymptote (bilateral), U — Mann–Whitney U-test.
Table 6. Comparison of patients with the clinical diagnoses of depression and “Other” based on biochemical indicators
Note: р — asymptote (bilateral), U — Mann–Whitney U-test.
