ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
Copyright: © 2026 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
ORIGINAL RESEARCH
Morphological and functional changes in the upper respiratory tract following rapid palatal expansion in adolescents
About authors
1 North Ossetian State University named after K.L. Khetagurov, Vladikavkaz, Russia
2 North Ossetian State Medical Academy, Vladikavkaz, Russia
Correspondence should be addressed: Oksana M. Mrikayeva
Vatutina, 44-46, Vladikavkaz, 362025, Russia, Republic of North Ossetia — Alania; ur.xednay@o-aveakirm
About paper
Author contribution: Mrikayeva OM — study concept and design, scientific guidance, text editing; Akhmatova FT, Kakaeva MR, Rasukhanova EU — collection of clinical material, database compilation, statistical processing, manuscript preparation; Elmurzaev SS-Kh, Dzhabrailov BKh, Yusupova ST, Tugueva SL, Idrisova SM — literature analysis, morphometry and functional measurements, manuscript formalization.
Compliance with ethical standards: the study was approved by the local Ethics Committee of North Ossetian State Medical Academy of the Ministry of Health of the Russian Federation (Minutes No. 4 of September 18, 2025). Parents or legal representatives have voluntarily signed informed consent forms for all underage participants; adolescents have consented to medical examination and the processing of anonymized data.
Received: 2026-03-19
Accepted: 2026-05-05
Published online: 2026-05-18
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Table 1. Dynamics of upper respiratory tract parameters after RPE
Note: the table shows relative changes from baseline for morphometric and functional indicators; for the NOSE survey, it shows absolute changes in points. Additionally, the total NOSE score decreased by 57.8% from baseline.
Table 2. Intergroup comparison of relative changes after RPE (pilot trial)
Note: relative changes from baseline are shown for indicators with the greatest differences in effect (by subgroups); some intergroup comparisons were not statistically significant.
