Copyright: © 2026 by the authors. Licensee: Pirogov University.
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ORIGINAL RESEARCH

Appropriateness of prescribing alfacalcidol in secondary hyperparathyroidism in dialysis patients: a retrospective study

Saadoon SJ1 , Atiyah AM2 , Ibrahim AH2 , Mostafa FM2
About authors

1 College of Pharmacy, University of Thi-Qar, Thi-Qar, Iraq

2 College of Pharmacy, Al-Ayen Iraqi University, AUIQ, An Nasiriyah, Iraq

Correspondence should be addressed: Fatma M. Mostafa
Thi-Qar, 64001, Iraq; moc.liamg@999888afatsomamtaf

About paper

Acknowledgements: the authors would like to thank the staff and administration of the hemodialysis units in An-Naseria, Iraq, for their cooperation and support in accessing patient records. The authors also express gratitude to the College of Pharmacy, University of Thi-Qar, and Al-Ayen Iraqi University for providing logistical support.

Author contribution: Fatma M. Mostafa — conceptualization, study design, data collection, data analysis, manuscript drafting, and final approval; Sarah Jaafar Saadoon — data collection, visualization, review, and manuscript revision; Ammar Mohammed Atiyah — data interpretation, statistical analysis (SPSS), and critical revision of the manuscript; Ahmed H. Ibrahim — data validation, manuscript editing, and final approval.

Compliance with ethical standards: this retrospective study was conducted in accordance with the ethical standards, the research was approved by the Research Ethics Committee of Al-Ayen Iraqi University under approval number AUIQ-REC-2025-003. Due to the retrospective nature of this study using anonymized patient records, the requirement for informed consent was waived by the ethics committee.

Received: 2026-04-13 Accepted: 2026-05-16 Published online: 2026-05-30
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Table 1. Demographic data & biochemical factors of secondary hyperparathyroidism patients
Table 2. Biochemical and dialysis variables in vitamin D indicated and non-indicated patients
Table 3. PTH level (pg/ml) in association with vitamin D indicated and not-indicated patients
Note: Chi-square test was utilized; * — P-value is significant.
Table 4. Corrected calcium level (mmol/l) in association with vitamin D indicated and not-indicated patients
Note: Chi-square test was utilized.
Table 5. Phosphorus level (mg/dl) in association with vitamin D indicated and not-indicated patients
Note: Chi-square test was utilized.