ISSN Print 2500–1094    ISSN Online 2542–1204
Bulletin of RSMU
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)

Yuriy V KOTELEVTSEV

Associate Director of Center for Functional Genomics and RNA therapy,
Skolkovo Institute of Science and Technology (Moscow, Russia)

CSc (chemistry)

Areas of expertise:

transgenic animals as a platform for modeling systemic diseases and therapeutic target discovery; atherosclerosis, hypertension, metabolic syndrome, non-alcoholic fatty liver disease (NAFDL)

Special awards and honors:

Winner of the first competition for Mega-grants (Russia)

ABOUT SCIENCE:

Significant publications in last 5 years

  1. Lenoir O, Milon M, Virsolvy A, Hénique C, Schmitt A, Massé JM, Kotelevtsev Y, et al. Direct action of endothelin-1 on podocytes promotes diabetic glomerulosclerosis. J Am Soc Nephrol. 2014 May; 25 (5): 1050–62. DOI: 10.1681/ASN.2013020195.
  2. Malekin SI, Kotelevtsev SV, Gavrilova SA, Fadyukova OE, Golubeva AV, Grinchenko MI, Koshelev VB, Kotelevtsev YV, Hamet P, Orlov SN. Long-term normalization of blood pressure in SHR and 1-kidney 1-clip rats by synthetic precursor of stable PAF analogue without systemic effects in normotensive rats. Pathophysiology. 2011 Apr; 18 (2): 151–7. DOI: 10.1016/j.pathophys.2010.08.001.
  3. Bailey MA, Craigie E, Livingstone DE, Kotelevtsev YV, Al-Dujaili EA, Kenyon CJ, Mullins JJ. Hsd11b2 haploinsufficiency in mice causes salt sensitivity of blood pressure. Hypertension. 2011 Mar; 57 (3): 515–20. DOI: 10.1161/HYPERTENSIONAHA.110.163782.
  4. Deuchar GA, McLean D, Hadoke PW, Brownstein DG, Webb DJ, Mullins JJ, Chapman K, Seckl JR, Kotelevtsev YV11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice. Endocrinology. 2011 Jan; 152 (1): 236–46. DOI: 10.1210/en.2010-0925.
  5. Kelland NF, Kuc RE, McLean DL, Azfer A, Bagnall AJ, Gray GA, Gulliver-Sloan FH, Maguire JJ, Davenport AP, Kotelevtsev YV, Webb DJ. Endothelial cell-specific ETB receptor knockout: autoradiographic and histological characterisation and crucial role in the clearance of endothelin-1. Can J Physiol Pharmacol. 2010 Jun; 88 (6): 644–51. DOI: 10.1139/Y10-041.