Bulletin of RSMU

ISSN Print 2500–1094 ISSN Online 2542–1204

BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)

Svistushkin VM, Egorov VI, Mustafaev DM, Volkova KB

Laryngeal papillomatosis is one of the important and unresolved problems of modern medicine. Tumor affects both children and adults, which is often fraught with serious life-threatening complications to the patient. The aim of the study was to evaluate the effectiveness of treatment of patients with laryngeal papillomatosis by using the combined method — cold plasma endolaryngeal microsurgery papillomas and inducers of an endogenous interferon therapy and activator of NK-killers (trade name Allokin-alpha) compared with the surgery without preventive treatment. The study included 50 patients, divided into two equal groups. In the study group, which consisted of 25 patients who received the combination treatment there increased an interrecurrent period and reduced the frequency of recuring. Thus, this method of treatment is recommended for the laryngeal papillomatosis.

Received: 2014-11-21

Published online: 2017-01-05

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Vasina AA, Radtsig EYu

Diseases of the vocal apparatus and state structures of the larynx are the least studied fields of pediatric otorhinolaryngology. Currently, the frequency of congenital abnormalities increases. This is due to the increase in the volume and improvement of the quality of diagnosis in childhood. This article describes the main methods of diagnosis of the larynx pathology, as well as data obtained by the authors in the study of its structure. There is described in details the structure of larynx pathology, which is characteristic for each age group, and there is traced its variation with age.

Received: 2014-11-21

Published online: 2017-01-05

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Kirichenko IM, Popadyuk VI

The article provides a brief review of the literature on the etiology and pathogenesis, clinic and methods of treatment of keloids. The clinical case of a large keloid of an auricle is considered. There was conducted a combined treatment of a patient with a positive clinical effect.

Received: 2014-11-21

Published online: 2017-01-05

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Svistushkin VM, Egorov VI, Zolotova AV, Shevchik EA

The aim of the work was to estimate the regeneration of the ear drum after the radiofrequency and laser myringotomy. 37 patients with otitis media with effusion were observed. In the 1st group (19 patients) perforation was performed using a radiofrequency device, in the 2nd group (18 patients) — with a laser. The evaluation of inflammatory changes of the tympanic membrane in the early postoperative period and the time of the perforation closure were estimated.

Received: 2014-11-21

Published online: 2017-01-05

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Baranov KK, Bogomilsky MR, Minasyan VS

This article presents an analytical review of the literature data and clinical observations of the authors on the actual problem of exacerbations of chronic suppurative otitis media in children. Contemporary possibilities of early diagnosis of the disease with high precision using a digital otoscope and computed tomography of the temporal bones were discussed. A rational approach to the treatment of chronic inflammatory diseases of the middle ear in terms of surgical technique was described. Presented methods of diagnosis and treatment allow not only to achieve the restoration of the affected anatomical structures of the middle ear, auditory function, but also to prevent otogenic complications in children.

Received: 2014-11-21

Published online: 2017-01-05

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Dobrokhotova YuE, Kheydar LA, Boyar EA, Sebko TV, Gvozdev AA, Filatova LA

The article shows the need for joint management of a pregnant woman suffering from the epilepsy by doctors of an obstetric-gynecologic profile and neurologists. It is emphasized the importance of prevention of fetal malformations, rational therapy of epilepsy during pregnancy and teratogenic hazard of antiepileptic drugs.

Received: 2014-10-07

Published online: 2017-01-05

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Makarov OV, Khashukoeva AZ, Kupeeva ES, Khlynova SA, Sukhova TN

The aim of the study was to evaluate the efficacy of photodynamic therapy in patients with dystrophic disease of the vulva. The method of photodynamic therapy using a photosensitizer fotoditazin is a promising one for the treatment of such diseases and can be an effective prevention of vulvar cancer.

Received: 2014-10-07

Published online: 2017-01-05

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Makarov OV, Narimanova MR

In this review of literature new tendencies in the questions of etiopathogenesis of ovarian cancer are highlighted. There are discussed some pathogenetic aspects in the progress of this pathology, such as proto-oncogenes and oncogenes. There are presented modern methods of screening and diagnostics of ovarian tumors. The opportunities of the application of biomarkers and their combinations for the early diagnostics of malignant ovarian neoplasms are discussed.

Received: 2014-10-07

Published online: 2017-01-05

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