ORIGINAL RESEARCH
Microcirculatory Bed of Myocardium in Non-Coronarogenic Heart Diseases
1 Department of Morphology, Faculty of Medicine and Biology,
Pirogov Russian National Research Medical University, Moscow, Russia
2 Institute for Fundamental and Applied Biomedical Research,
Pirogov Russian National Research Medical University, Moscow, Russia
Correspondence should be addressed: ValeriaTsyplenkova
ul. Ostrovityanova, d. 1, Moscow, Russia, 117997; ur.liam@nekcihclav
On the material of endomyocardial and intraoperation biopsies from patients with noncoronarogenic heart diseases (dilated and diabetic cardiomiopathies, paroxysmal arrhythmia, arrhythmogenic right ventricular dysplasia) on semithin and ultrathin sections there was studied myocardial microcirculation bed. By morphometry there was found the decrease of capillaries density of myocardial bed, degenerative changes in endothelial cells and microthrombosis. It was supposed that these changes are the factors of progression of heart failure.
Keywords: cardiomyopathy, myocardium, ultrastructure, microcirculation