2017 / 03

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DOI: 10.24075/brsmu.2017-03-05

OPINION

The prospects of gene therapy for mitochondrial diseases: can’t we do without CRISPR/Cas9?

Chicherin IV, Levitskii SA1, Krasheninnikov IA, Tarassov I2, Kamenski P3
About authors

1 Faculty of Biology, Lomonosov Moscow State University, Moscow

2 Laboratory of Molecular Genetics, Genomics and Microbiology,
University of Strasbourg, Strasbourg, France

3 Institute of Living Systems,
Immanuel Kant Baltic Federal University, Kaliningrad, Russia

Correspondence should be addressed: Peter Kamenski
Leninskie Gory, d. 1, str. 12, Moscow, Russia, 119991 (Faculty of Biology); ur.usm.oib.nietorp@retep

About paper

Funding: Russian Science Foundation, grant No. 14-50-00029 (Lomonosov Moscow State University); Project 5–100 of the Ministry of Education and Science of the Russian Federation (Immanuel Kant Baltic Federal University); the International Associated Laboratory RNA-mitocure (Lomonosov Moscow State University and the University of Strasbourg).

Contribution of the authors to this work: Chicherin IV, Levitsky SA —analysis of literature; Krasheninnikov IA, Tarassov I — analysis of mechanism of a hypothetical mitoCRISPR/Cas9 platform; Kamenski P — data generalization, drafting of a manuscript. All authors participated in editing of the manuscript.

Received: 2017-06-20 Accepted: 2017-06-23 Published online: 2017-07-19
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