Funding: this work was supported by the Ministry of Education and Science of the Russian Federation, Project ID RFMEFI60716X0158.

Acknowledgements: we are grateful to the patient who has kindly given his consent to participate in the study; to Denis Fedorenko, a hematologist and Professor of Maximov Hematology and Cell Therapy Department (Pirogov National Medical Surgical Center) for his consultations; Elena Kovalenko, a senior researcher at Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, for her assistance in conducting a flow cytometry analysis.