ISSN Print 2500–1094
ISSN Online 2542–1204
Bulletin of RSMU
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
Comparison of fluorescence excitation modes for cdse semi-conductor quantum dots used in medical research
About authors
1 Department of Physics of Micro- and Nanosystems, National Research Nuclear University MEPhI, Moscow
2 Laboratory of Nano-Bioengineering, National Research Nuclear University MEPhI, Moscow
Correspondence should be addressed: Yuri A. Kuzishchin
Kashirskoe highway, 31, Moscow, 115409; moc.liamg@nihchsizuk.yiry
About paper
Funding: this work was supported by the Federal Target Program The National System for Chemical and Biological Security of the Russian Federation (2015– 2020) and carried out under the state contract No. K-27-НИР/146-2 dated December 28, 2015 signed by the Ministry of Healthcare of the Russian Federation and the National Research Nuclear University MEPhI.
Received: 2018-07-29
Accepted: 2018-08-25
Published online: 2018-10-09
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Fig. 1. Dependency of the signal-to-noise ratio of the receiver on the background noise power in the modulated excitation mode (1) and pulsed excitation mode (2) for a luminophore with an excited-state lifetime of 1 ns (2), 10 ns (3), and 100 ns (4). (A) Signal accumulation times is 1 ms, the average power of the fluorescent signal is 1 nW, the typical frequency of background fluctuations is 100 Hz. (B) Signal accumulation times is 1,000 ms, the average power of the fluorescent signal is 1 nW, the typical frequency of background fluctuations is 100 Hz
Fig. 2. Dependency of the signal-to-noise ratio of the receiver on the background noise power in the modulated excitation mode (1) and pulsed excitation mode (2) at typical frequencies of the background power fluctuation of 10 Hz (1), 100 Hz (2), and 1,000 Hz (4). (A) Signal accumulation times is 1 ms, the average power of the fluorescent signal is 1 nW, the excited-state lifetime of the luminophore is 10 ns. (B) Signal accumulation times is 1,000 ms, the average power of the fluorescent signal is 1 nW, the excited-state lifetime of the luminophore is 10 ns
