2018 / 06

Следующая статья
DOI: 10.24075/vrgmu.2018.081

ОБЗОР

Адресная доставка лекарственных нанопрепаратов в применении к моделям рака на доклиническом этапе исследований

C. Марчио1,2, Ф. Буссолино1,2
Информация об авторах

1 Кафедра онкологии, Туринский университет, Кандиоло, Италия

2 Институт онкологии(FPO-IRCCS), Кандиоло, Италия

Для корреспонденции: Серена Марчио
Институт исследований и лечения рака, Университет Турина, 142 Kм 3.95, Кaндиоло, Италия, 10060; ti.ccri@oihcram.aneres

Статья получена: 29.06.2018 Статья принята к печати: 21.08.2018 Опубликовано online: 30.12.2018
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  1. Arap W, Pasqualini R, Montalti M, Petrizza L, Prodi L, Rampazzo E et al. Luminescent silica nanoparticles for cancer diagnosis. Curr Med Chem. 2013; 20 (17): 2195–211.
  2. Bobo D, Robinson KJ, Islam J, Thurecht KJ, Corrie SR. Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date. Pharm Res. 2016; 33 (10): 2373–87.
  3. Caster JM, Patel AN, Zhang T, Wang A. Investigational nanomedicines in 2016: a review of nanotherapeutics currently undergoing clinical trials. Rev Nanomed Nanobiotechnol. 2017; 9 (1): e1456.
  4. Marchiò S, Soster M, Cardaci S, Muratore A, Bartolini A, Barone V et al. A complex of alpha(6) integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6. EMBO Mol Med. 2012 Nov; 4 (11): 1156–75.
  5. Soster M, Juris R, Bonacchi S, Genovese D, Montalti M, Rampazzo E et al. Targeted dual-color silica nanoparticles provide univocal identification of micrometastases in preclinical models of colorectal cancer. Int J Nanomed. 2012; (7): 4797–807.
  6. Bonacchi S, Genovese D, Juris R, Montalti M, Prodi L, Rampazzo E et al. Luminescent chemosensors based on silica nanoparticles. Top Curr Chem. 2011; (300): 93–138.
  7. Bonacchi S, Genovese D, Juris R, Montalti M, Prodi L, Rampazzo E et al. Luminescent silica nanoparticles: extending the frontiers of brightness. Angew Chem Int Ed Engl. 2011; 50 (18): 4056–66.
  8. D'Hallewin MA, Kamuhabwa AR, Roskams T, De Witte PA, Baert L. Hypericin-based fluorescence diagnosis of bladder carcinoma. BJU Int. 2002; 89 (7): 760–3.
  9. Miyashiro I, Miyoshi N, Hiratsuka M, Kishi K, Yamada T, Ohue M et al. Detection of sentinel node in gastric cancer surgery by indocyanine green fluorescence imaging: comparison with infrared imaging. Ann Surg Oncol. 2008; 15 (6): 1640–3.
  10. van Dam GM, Themelis G, Crane LM, Harlaar NJ, Pleijhuis RG, Kelder W et al. Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-alpha targeting: first in-human results. Nat Med. 2011; 17 (10): 1315–9.
  11. van der Poel HG, Buckle T, Brouwer OR, Valdes Olmos RA, van Leeuwen FW. Intraoperative laparoscopic fluorescence guidance to the sentinel lymph node in prostate cancer patients: clinical proof of concept of an integrated functional imaging approach using a multimodal tracer. Eur Urol. 2011; 60 (4): 826–33.
  12. de Leeuw J, van der Beek N, Neugebauer WD, Bjerring P, Neumann HA. Fluorescence detection and diagnosis of non-melanoma skin cancer at an early stage. Lasers Surg Med. 2009; 41 (2): 96–103.
  13. Atlamazoglou V, Yova D, Kavantzas N, Loukas S. Microscopical examination of the localisation patterns of two novel rhodamine derivatives in normal and neoplastic colonic mucosa. Lasers Med Sci. 2001; 16 (4): 253–9.
  14. Marchiò S, Lahdenranta J, Schlingemann RO, Valdembri D, Wesseling P, Arap MA et al. Aminopeptidase A is a functional target in angiogenic blood vessels. Cancer Cell. 2004; 5 (2): 151–62.
  15. Pasqualini R, Koivunen E, Kain R, Lahdenranta J, Sakamoto M, Stryhn A. Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis. Cancer Res. 2000; 60 (3): 722–7.
  16. Loi M, Di Paolo D, Soster M, Brignole C, Bartolini A, Emionite L et al. Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings. J Control Release. 2013; 170 (2): 233–41.
  17. Cossu I, Bottoni G, Loi M, Emionite L, Bartolini A, Di Paolo D et al. Neuroblastoma-targeted nanocarriers improve drug delivery and penetration, delay tumor growth and abrogate metastatic diffusion. Biomaterials. 2015; (68): 89–99.
  18. Loi M, Marchiò S, Becherini P, Di Paolo D, Soster M, Curnis F et al. Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma. J Control Release. 2010; 145 (1): 66–73.