2019 / 05

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DOI: 10.24075/brsmu.2019.072

ORIGINAL RESEARCH

Correlated dynamics of serum IGE and IGE+ clonotype count with allergen air level in seasonal allergic rhinitis

Mikelov AI1, Staroverov DB, Komech EA3, Lebedev YuB3, Chudakov DM1,3, Zvyagin IV3
About authors

1 Skoltech, Moscow, Russia

2 Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia

3 Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Ivan V. Zvyagin
Miklukho-Maklaya, 16/10, Moscow, 117997; moc.liamg@nigayvzi

About paper

Funding: the study was supported by the Grants Council under the President of the Russian Federation (grant MK6000.2018.4).

Acknowledgments: we are very grateful to all the donors who participated in the study.

Author contribution: Mikelov AI — antibody levels determination, IGH cDNA libraries preparation, sequencing data and results analysis, research design, drafting; Staroverov DB — cell subpopulations isolation (flow cytofluorometry); Komech EA — blood samples collection, cell subpopulations isolation (flow cytofluorometry); Lebedev YB — results analysis and discussion, advisory support; Chudakov DM — results analysis and discussion, advisory support (cDNA libraries preparation); Zvyagin IV — IGH cDNA libraries preparation,sequencing data and results analysis, research design, drafting, research organization.

Received: 2019-10-09 Accepted: 2019-10-23 Published online: 2019-10-31
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