Funding: this work supported by the Russian Science Foundation (Grant 19-15-00320).

Acknowledgement: the authors thank their colleagues, Olshansky AS and Yamshchikova NG (the Laboratory of Experimental Pathology of the Nervous System), for their valuable contribution.

Author contribution: Stavrovskaya AV planned the study, analyzed the literature, collected, analyzed and interpreted the obtained data, conducted behavioral tests, administered drugs to the animals, and prepared the draft of the manuscript; Voronkov DN analyzed the literature, analyzed and interpreted the obtained data, prepared brain slides, conducted the histopathologic examination, and prepared the draft of the manuscript; Kutukova KA analyzed the literature, analyzed the obtained data, prepared jejunum slides, carried out the histopathologic examination, and prepared the draft of the manuscript; Ivanov MV prepared jejunum slides and carried out the histopathologic examination; Gushchina AS collected data, administered drugs to the rats, carried out behavioral tests, and monitored the animals’ health as a vet; Illarioshkin SN supervised the study and prepared the draft of the manuscript.