2020 / 02

Next Paper
DOI: 10.24075/brsmu.2020.024

ORIGINAL RESEARCH

Role of ACE2/TMPRSS2 genes regulation by intestinal microRNA isoforms in the COVID-19 pathogenesis

Nersisyan SA1,2, Shkurnikov MYu3, Osipyants AI3,4, Vechorko VI5
About authors

1 National Research University Higher School of Economics, Moscow, Russia

2 Lomonosov Moscow State University, Moscow, Russia

3 P. A. Hertsen Moscow Oncology Research Center, branch of the National Medical Research Radiology Center, Moscow, Russia

4 Far Eastern Federal University, Vladivostok, Russia

5 City Clinical Hospital № 15 named after O. M. Filatov, Moscow, Russia

Correspondence should be addressed: Stepan A. Nersisyan
Vavilova, 7, Moscow, 117312; moc.liamg@naysisren.a.s

About paper

Funding: the study was supported by the Ministry of Science and Higher Education of the Russian Federation grant (project RFMEFI61618X0092).

Author contribution: Nersisyan SA, Shkurnikov MYu, Osipyants AI, Vechorko VI — study concept; Nersisyan SA, Shkurnikov MYu — bioinformatics analysis; Nersisyan SA, Shkurnikov MYu, Osipyants AI, Vechorko VI — interpretation of results; Nersisyan SA — manuscript writing.

Received: 2020-04-17 Accepted: 2020-04-28 Published online: 2020-04-29
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Fig. ACE2 and TMPRSS2 expression distribution in the colon tissues. Borders of the boxes correspond to the lower and upper quartiles, vertical segment inside the box represents the median value