ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
Interactions between gene pools of russian and finnish-speaking populations from Tver region: analysis of 4 million SNP markers
About authors
1 Vavilov Institute of General Genetics, Moscow, Russia
2 Research Center for Medical Genetics, Moscow, Russia
3 Biobank of North Eurasia, Moscow, Russia
4 Federal Research and Clinical Center of Physical-Chemical Medicine, Moscow, Russia
Correspondence should be addressed: Oleg P. Balanovsky
Gubkina, 3, Moscow, 119991; ur.xobni@yksvonalab
About paper
Funding: the study was supported by the Russian Ministry and Science and Higher Education (Government Contact # 011–17 dated September 26, 2017). Genotyping and manuscript preparation were done under the DNA-based identification Research and Technology Project of the Union State. Bioinformatic analysis and interpretation of the obtained results were carried out under the State Assignment of the Russian Ministry of Science and Higher Education for Bochkov Research Centre for Medical Genetics.
Acknowledgement: we thank all the donors who took part in this study, the Biobank of North Eurasia for DNA collections and Napolskikh VV, the corresponding member of RAS, for his contribution to data interpretation.
10.24075/brsmu.2020.072
Received: 2020-10-10
Accepted: 2020-10-27
Published online: 2020-11-26
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Fig. 1. The geographical map of the studied Tver region populations. Circles represent places of birth for each of 4 ancestors (2 grandmothers and 2 grandfathers) of each participant; Tver Karels are shown in red; East Tver Russians are shown in blue; South Tver Russians are shown in green; West Tver Russians are shown in yellow
Fig. 2. The principal component plot showing genetic variance in the studied
populations. KARn — North Karels, KARs — South Karels, KARt — Tver Karels,
RCN — Novgorod Russians, RCTk — Tver Russians of Kashin (East), RCTt —
Tver Russians of Torzhok (South), RCTs — Tver Russians of Selizharovo (West),
RCY — Yaroslavl Russians, RNP — Pskov Russian, RNV — Vologda Russians.
Individual samples are marked by small circles; centroids (centers of gravity for
each population) are marked by larger circles of the same color
Fig. 3. The ADMIXTURE chart (contributions of ancestral components to the studied populations (at different k values). Profiles of individual samples are provided in
separate columns; individual samples representing different populations are separated by vertical bars
Table. The contributions of ancestral ADMIXTURE components to the studied populations (at different k values)
