ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
Brain atrophy patterns in patients with frontotemporal dementia: voxel-based morphometry
About authors
1 Research Center of Neurology, Moscow, Russia
2 Sechenov First Moscow State Medical University, Moscow, Russia
3 Pirogov Russian National Research Medical University, Moscow, Russia
Correspondence should be addressed: Dilyara R. Akhmadullina
Volokolamskoye shosse, 80, Moscow, 125367; moc.liamg@1rdanilludamhka
About paper
Funding: the study was supported by the Russian Foundation for Basic Research (grant № 19-015-00533).
Author contribution: Akhmadullina DR — clinical assessment, data analysis and interpretation, literature analysis, manuscript writing; Konovalov RN — data analysis and interpretation, study planning and management; Shpilyukova YuA, Grishina DA — clinical assessment, manuscript draft preparation; Berdnikovich ES — clinical assessment; Fomenko SS — data analysis and interpretation, literature analysis, manuscript writing; Fedotova EYu — study planning and management; Illarioshkin SN — study planning and management.
Received: 2020-10-21
Accepted: 2020-11-18
Published online: 2020-12-08
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Fig. Localization of significant (pFWE-corr < 0.05) GM volume decline in patients with FTD compared to control group. А. Lleft inferior frontal gyrus. B. Left supramarginal gyrus. C. Left fusiform gyrus. From left to right: sagittal, axial and coronal slices
Table 1. Areas of significant (pFWE-corr < 0.05) gray matter volume reduction based on VBM data
Note: S — left.
Table 2. Gray matter volume in patients with FTD and control group
Note: LQ — lower quartile, UQ — upper quartile, S — left, D — right.
