ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
Copyright: © 2021 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
ORIGINAL RESEARCH
Refinement of noninvasive methods for diagnosing precancer and cancer of oral mucosa in general dental practice
About authors
1 Samara State Medical University, Samara, Russia
2 Samara Regional Clinical Cancer Center, Samara, Russia
3 Pirogov Russian National Research Medical University, Moscow, Russia
Correspondence should be addressed: Alexey G. Gabrielyan
Michurina, 138, kv. 85, Samara, 443086; ur.liam@200_leirbag
About paper
Author contribution: Postnikov MA — literature analysis; Gabrielyan AG — study planning; Trunin DA, Kopetskiy IS, Eremin DA — analysis of the obtained data; Kaganov OI — manuscript draft; Kirillova VP — analysis of patients’ records; Khamadeeva AM — interpretation of the obtained results; Osokin OV — data acquisition.
Compliance with ethical standards: the study was approved by the Ethics Committee of Samara State Medial University (Protocol № 27 dated February 12, 2018).
Received: 2020-12-18
Accepted: 2021-01-29
Published online: 2021-02-17
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Fig. 1. An algorithm for assessing indications for biopsy in patients with vermillion lip border and oral mucosa neoplasia presenting to a dentist for a clinical examination
Fig. 2. Biopsy of a buccal mucosa lesion
Fig. 3. Lingual mucosa lesion detected on clinical examination
Fig. 4. Brown autofluorescence of lingual mucosa under AFS400 light
Fig. 5. Distribution of presenting complaints in the main (M1) and control (M2) groups on clinical examination
Fig. 6. Distribution of patients in the groups by histologically verified diagnoses
Fig. 7. Distribution of patients in the groups by cancer stages
Table 1. Lesions sites in the main and control groups
Note: Pearson’s coefficient = 2.7567; р = 0.8386.
Table 2. Presenting complaints in the main (M1) and control (M2) groups
Table 3. Clinical manifestations detected on examination in the main (M1) and control (M2) groups (under natural light)
