Author contribution: Ivashchenko AV, Postnikov MA collected and analyzed clinical data; Tlustenko VP did organizational work and conducted the experiment; performed systematic analysis; Popov NV performed statistical analysis of the obtained data; Yablokov AE did organizational work and conducted the experiment, collected and analyzed clinical data; Tlustenko VS analyzed clinical data. Tugushev VV, Cherezova NI, Mukhina AA did organizational work and conducted the experiment; Belanov GN — sistematic analysis.

Compliance with ethical standards: the study was approved by the Ethics Committee of Samara State Medical University (Protocol 209 dated February 3, 2021).