2021 / 04

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DOI: 10.24075/brsmu.2021.035

ORIGINAL RESEARCH

Role of mast cells in skin regeneration after thermal burn treated with melatonin-enriched dermal film

Osikov MV1,2, Ageeva AA1, Fedosov AA3, Ushakova VA1
About authors

1 South-Ural State Medical University, Chelyabinsk, Russia

2 Chelyabinsk Regional Clinical Hospital, Chelyabinsk, Russia

3 Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Anna A. Ageeva
Vorovskogo, 64, Chelyabinsk, 454092; ur.xednay@r.aveega.enna

About paper

Funding: the study was supported by the Russian Foundation for Basic Research and the government of Chelyabinsk region (Project ID 20-415-740016).

Author contribution: Osikov MV — study concept and design; integral analysis of the obtained data; manuscript preparation and editing; Ageeva AA — data acquisition; statistical analysis; analysis of study results; manuscript preparation; Fedosov AA — analysis of study results; manuscript editing; Ushakova VA — synthesis of the dermal film; analysis of study results.

Compliance with ethical standards: the study was approved by the Ethics Committee of South-Ural State Medical University (Protocol № 10 dated November 15, 2019). The study was conducted at a standard vivarium in strict compliance with guidelines on the care and euthanasia of laboratory animals outlined in the European Convention for the Protection of Vertebrate Animals used for Experimental and other Scientific Purposes (ETS № 123 , March 18, 1986, Strasburg), the EU Commission Recommendation 2007/526/EC on Guidelines for the Accommodation and Care of Animals used for Experimental and other Scientific Purposes (June 18, 2007), and the Directive 2010/63/EU of the European Parliament and of the Council on the Protection of Animals used for Scientific Purposes (September 22, 2010).

Received: 2021-06-28 Accepted: 2021-07-12 Published online: 2021-08-07
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