Author contribution: Gumenyuk LN, Sorokina LE — significant contribution to the study concept and design; Golod MV, Silaeva NV, Androschyuk NA — data acquisition, analysis, and interpretation; Ilyasov SS — statistical data processing; Krivoshapko OR, Velilyaev AM, Asanova LN — manuscript writing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University (protocol № 11 dated November 23, 2021), planned and conducted in accordance with the Declaration of Helsinki. The informed consent was obtained from all study participants.