Funding: the study was carried out as a part of "Molecular pharmacological markers of recurrence for proliferative processes of the reproductive tract tissues in postmenopausal patients" 2018–2020 research project at the Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia (universal decimal classifier 577.21; R&D No. АААА-А18-118051590095-4; info reg. ID No. АААА-Б20-220100690049-5)

Author contribution: Savelieva GM — design and supervision; Breusenko VG — clinical supervision; Kareva EN — laboratory supervision, laboratory tests and analysis of the data; Golukhov GN — consulting, data interpretation, manuscript editing; Gutorova DS — concept, patient database construction, statistical processing, analysis and interpretation of the data, manuscript writing; Ovchinnikova AV — statistical processing of the data; Ivanovskaya TN — formal analysis; Shcherbatyuk KV — patient data management.

Compliance with ethical standards: the study was approved by Ethical Review Board at the Pirogov Russian National Research Medical University (Protocol № 210 of 30 August 2021). All patients provided voluntary informed consent for the study.