ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
Copyright: © 2022 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
ORIGINAL RESEARCH
EPOR/CD131-mediated attenuation of rotenone-induced retinal degeneration is associated with upregulation of autophagy genes
About authors
1 Belgorod State National Research University, Belgorod, Russia
2 Sechenov First Moscow State Medical University, Moscow, Russia
3 Kursk State Medical University, Kursk, Russia
4 Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
Correspondence should be addressed: Vladislav O. Soldatov
Pobedy, 85, Belgorod, 308015, Russia; moc.liamg@votadlosmrahp
About paper
Funding: State Assignment "Laboratory for Genome Editing in Biomedicine and Veterinary FZWG-2021-0016".
Author contribution: Soldatov VO — concept and design of the study, writing of the manuscript; Pokrovsky MV, Lapin KN — consulting on the concept and design of the study; Puchenkova OA — collection of samples for histological examination and target gene expression analysis; Puchenkova OA, Zhunusov NS — modeling of the rotenone-induced retinal degeneration; Zhunusov NS, Krayushkina AM — in vitro assay of rotenone cytoprotective activity; Grechina AV — morphological study; Bushueva OYu, Soldatova MO — RNA extraction, quantitative PCR assay.
Compliance with ethical standards: the study was approved by the ethical committee of the Belgorod State National Research University (Protocol № 06-07/21 of 15 July 2021); all procedures were performed in accordance with the Regulations on Laboratory Practice in the Russian Federation of 2003, in compliance with the 86/609 EEC Directive and ARRIVE guidelines.
Received: 2022-07-11
Accepted: 2022-08-01
Published online: 2022-08-12
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