Author contribution: Vagner VD — planning of the study, literature analysis, data interpretation; Sarf EA — biochemical research, statistical analysis; Belskaya LV — planning of the study, biochemical research, manuscript preparation; Korshunov AS — planning of the study, literature analysis, data interpretation, collection of clinical samples, manuscript preparation; Kuryatnikov KN — collection of clinical samples, data interpretation, manuscript preparation; Bondar AA, Meloyan AD, Maksimenko KA, Kasiy MN — sample preparation, data analysis.

Compliance with ethical standards: the study was approved by ethical review board of the Omsk State Medical University (Protocol № 113 of 26 November 2019); all participants or their representatives provided informed consent for participation in the study.