2022 / 05

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DOI: 10.24075/brsmu.2022.050

ORIGINAL RESEARCH

Comparative assessment of RMI-IV and RMI-V in preoperative prediction of ovarian tumor type in pregnant women

Gerasimova AA1, Shevchenko YuV1, Klimenko PA2, Asyrafyan LA3
About authors

1 Center of Family Planning and Reproduction of the Moscow Healthcare Department, Moscow, Russia

2 Pirogov Russian National Research Medical University, Moscow, Russia

3 Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia

Correspondence should be addressed: Pyotr A. Klimenko
Sevastolopsky prospect, 24а, Moscow, 117209, Russia; ur.liam@oknemilk.ap

About paper

Author contribution: the authors contributed equally to the study and manuscript writing, read and approved the final version of the paper prior to publishing.

Compliance with ethical standards: the study was approved by the Ethics Committee of Pirogov Russian National Research Medical University (protocol № 176 of 25 June 2018). All patients submitted the informed consent to study participation.

Received: 2022-09-27 Accepted: 2022-10-12 Published online: 2022-10-24
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Fig. 1. Frequency analysis of RMI-IV and RMI-V in the surveyed pregnant women
Fig. 2. ROC-curves characterizing sensitivity and specificity of CA-125, RMI-IV and RMI-V as predictors of the successful diagnosis of malignant ovarian tumors in pregnant women
Table 1. Distribution of ovarian tumor histological types in pregnant women
Table 2. Descriptive statistics of СА-125 and Risk of Malignancy indices (RMI-IV and RMI-V) in pregnant women with benign, borderline and malignant ovarian tumors