ISSN Print 2500–1094
ISSN Online 2542–1204
BIOMEDICAL JOURNAL OF PIROGOV UNIVERSITY (MOSCOW, RUSSIA)
ORIGINAL RESEARCH
Antibacterial, anti-adhesive and anti-biofilm-forming activity of plant complexes against periodontopathogenic bacteria in vitro
About authors
1 Samara State Medical University, Samara, Russia
2 Military Medical Academy named after S.M.Kirov, St. Petersburg, Russia
3 Saint-Petersburg Pasteur Institute, St. Petersburg, Russia
4 ROMASHKA dental shop, department of scientific research, St. Petersburg, Russia
5 Pirogov Russian National Research Medical University, Moscow, Russia
6 Korolev Samara State University, Samara, Russia
Correspondence should be addressed: Alexey N. Sharov
Nevsky Prospekt, 46, Saint Petersburg, Russia; ur.xelavorahs@em
About paper
Acknowledgements: authors thank SS Astashova, illustrator with the Academy of Chlorophyll and Aspen Bark journal, for preparing photos and tables for this publication.
Author contribution: Kraeva LA, Khamdulayeva GN, Nosova MA — concept and design of the study; Latif II, Sharov AN — literature analysis, data collection and processing; Kraeva LA — statistical processing; Kraeva LA, Sharov AN, Latif II — manuscript drafting; Kopetsky IS, Eremin DA, Postnikova EV, Postnikov MA — editing.
Compliance with ethical standards: the study was approved by the Samara State Medical University's Ethics Committee (Minutes # ... of January 10, 2022)
Received: 2023-06-16
Accepted: 2023-08-08
Published online: 2023-08-24
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Fig. 1. Investigation of antibacterial properties of plant-based complexes. 1 — mouthwash; 2 — gel with chlorophyll, aspen bark and DHQ (Gel 2); 3 — gel with chlorophyll and chlorhexidine (Gel 1); 4 — oil with chlorophyll (Phytolone oil); 5 — oil with carotenoids from fir needles (Provitam oil); 6 — gel with chlorophyll and chlorhexidine (Gel 3); 7 — dental elixir with aspen bark extract and chlorophyll (Elixir)
Fig. 2. Biofilm formation preventing properties: Gel 1 vs. S. sanguinis. A. Colonies of S. sanguinis before application of gel with chlorophyll and chlorhexidine. B. Colonies of S. sanguinis after application of gel with chlorophyll and chlorhexidine (magnification ×400)
Fig. 3. Biofilm formation preventing properties: mouthwash vs. S. mitis. A. Colonies of S. mitis before use of mouthwash. B. Colonies of S. mitis after use of mouthwash
Fig. 4. Biofilm formation preventing properties: Provitam oil vs. S. oralis. A. Colonies of S. oralis before application of oil with fir needle carotenoids. B. Colonies of S. oralis after application of oil with fir needle carotenoids
Table 1. Investigation of antibacterial properties of plant-based complexes
Note: 1 — mouthwash; 2 — gel with chlorophyll, aspen bark and DHQ (Gel 2); 3 — gel with chlorophyll and chlorhexidine (Gel 1); 4 — oil with chlorophyll (Phytolone oil); 5 — oil with carotenoids from fir needles (Provitam oil); 6 — gel with chlorophyll and chlorhexidine (Gel 3); 7 — dental elixir with aspen bark extract and chlorophyll (Elixir)
Table 2. Investigation of adhesion preventing properties of plant-based complexes
Note: 1 — mouthwash; 2 — gel with chlorophyll, aspen bark and DHQ (Gel 2); 3 — gel with chlorophyll and chlorhexidine (Gel 1); 4 — oil with chlorophyll (Phytolone oil); 5 — oil with carotenoids from fir needles (Provitam oil); 6 — gel with chlorophyll and chlorhexidine (Gel 3); 7 — dental elixir with aspen bark extract and chlorophyll (Elixir).
