Author contribution: Korshunov AS — study planning, literature analysis, data interpretation, clinical data acquisition, manuscript writing; Vagner VD — study planning, literature analysis, data interpretation; Belskaya LV — study planning, biochemical investigations, manuscript writing; Kuryatnikov KN — clinical data acquisition, literature analysis, data interpretation, manuscript writing; Serov DO — clinical data acquisition, data interpretation, literature analysis; Krasnov VA — clinical data acquisition, sample preparation for assessment; Tigranyan GO, Bondar IA — sample preparation for assessment, data analysis.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Omsk State Medical University (extract from the protocol № 113 of 26 November 2019); the informed consent was submitted by all study participants or their legal representatives.