ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ
Аминокислотный профиль при сниженном овариальном резерве
1 Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени В. И. Кулакова, Москва, Россия
2 ФГБОУ ВО «Сибирский государственный медицинский университет», Минздрава России, Томск, Россия
Для корреспонденции: Алла Анатольевна Гависова
ул. Академика Опарина, д. 4, г. Москва, 117997, Россия; ur.ay@allaivag
Вклад авторов: А. А. Гависова — дизайн исследования, сбор и обработка материала, написание статьи, редактирование; М. А. Шевцова, Д. А. Бирюкова, П. О. Львова — дизайн исследования, сбор и обработка материала, обзор литературы, написание статьи, редактирование; А. В. Новоселова, М. Н. Юшина — разработка метода ЖХ-МС анализа аминокислот в плазме крови и фолликулярной жидкости, обработка экспериментальных данных; М. Х. Ибрагимова — сбор материала, редактирование; В. В. Чаговец, В. Е. Франкевич — статистическая обработка материала, редактирование.
Соблюдение этических стандартов: исследование одобрено этическим комитетом ФГБУ «НМИЦ АГП имени В. И. Кулакова» (протокол № 12от 25 ноября 2021 г.).
- Hu S. Perinatal outcome in young patients with diminished ovarian reserve undergoing assisted reproductive technology / S. Hu, B. Xu, L. Jin // Fertility and Sterility. 2020; 114 (1): 118–124.e1.
- Collado-Fernandez E, Picton HM, R. Dumollard ColladoFernandez E. Metabolism throughout follicle and oocyte development in mammals. The International Journal of Developmental Biology. 2012; 56 (10-11-12): 799–808.
- Dillin A, Gottschling DE, T. Nyström Dillin A. The good and the bad of being connected: the integrons of aging. Current Opinion in Cell Biology. 2014; 26: 107–12.
- Yang J, Feng T, Li S, et al. Human follicular fluid shows diverse metabolic profiles at different follicle developmental stages. Reproductive Biology and Endocrinology. 2020; 18 (1): 74.
- Moslehi N, Mirmiran P, Marzbani R. et al. Serum metabolomics study of women with different annual decline rates of antiMüllerian hormone: an untargeted gas chromatography–mass spectrometry-based study. Human Reproduction. 2021; 36 (3): 721–33.
- Shevtsova SMA, Gavisova GAA, Krasnova KNA, et al. Amino acid profile of blood plasma and follicular fluid in women with infertility and diminished ovarian reserve. Akusherstvo i ginekologiia. 2024; 2 (2024): 79–88.
- Клинические рекомендации «Женское бесплодие». 2021.
- RStudio Team. RStudio: Integrated Development for R. RStudio, Inc., Boston, MA; 2016. Available from: http://www.rstudio.com/.
- Misra BB. Data normalization strategies in metabolomics: Current challenges, approaches, and tools. European Journal of Mass Spectrometry. 2020; 26 (3): 165–74.
- Zhang X, Yoshihara K, Miyata N, et al. Dietary tryptophan, tyrosine, and phenylalanine depletion induce reduced food intake and behavioral alterations in mice. Physiology & Behavior. 2022; 244: 113653.
- Deanfield JE, Halcox JP, Rabelink TJ. Endothelial Function and Dysfunction. Circulation. 2007; 115 (10): 1285–95.
- Li J, Zhang Z, Wei Y, et al. Metabonomic analysis of follicular fluid in patients with diminished ovarian reserve. Frontiers in Endocrinology. 2023; 14. DOI: 10.3389/fendo.2023.1132621.
- Ross AC, Caballero BH, Cousins RJ, et al. Modern nutrition in health and disease: Eleventh edition. Wolters Kluwer Health Adis (ESP). 2012; 1616 p.
- Rasmussen DD, Ishizuka B, Quigley ME, Yen SSC. Effects of tyrosine and tryptophan ingestion on plasma catecholamine and 3,4-dihydroxyphenylacetic acid concentrations. The Journal of Clinical Endocrinology & Metabolism. 1983; 57 (4): 760–3.
- van Overveld F. W. P. C., Haenen G. R. M. M., Rhemrev J, et al. Tyrosine as important contributor to the antioxidant capacity of seminal plasma. Chemico-Biological Interactions. 2000; 127 (2): 151–61.
- Dubé F, Amireault P. Local serotonergic signaling in mammalian follicles, oocytes and early embryos. Life Sciences. 2007; 81 (25–26): 1627–37.
- Liu A, Shen H, Li Q, et al. Determination of tryptophan and its indole metabolites in follicular fluid of women with diminished ovarian reserve. Scientific Reports. 2023; 13 (1): 17124.
-
DuPont JJ, Farquhar WB, Townsend RR, Edwards DG. Ascorbic acid or
l -arginine improves cutaneous microvascular function in chronic kidney disease. Journal of Applied Physiology. 2011; 111 (6): 1561–7. - Takasaki A, Tamura H, Miwa I, et al. Endometrial growth and uterine blood flow: a pilot study for improving endometrial thickness in the patients with a thin endometrium. Fertility and Sterility. 2010; 93 (6): 1851–8.
- Luo Y, Zhu Y, Basang W, et al. Roles of nitric oxide in the regulation of reproduction: a review. Frontiers in Endocrinology. 2021; 12.
-
Kopets R, Kuibida I, Chernyavska I, et al. Dietary supplementation with a novel
l ‐carnitine multi‐micronutrient in idiopathic male subfertility involving oligo‐, astheno‐, teratozoospermia: a randomized clinical study. Andrology. 2020; 8 (5): 1184–93. - D’Aniello G, Grieco N, Di Filippo MA, et al. Reproductive implication of D-aspartic acid in human pre-ovulatory follicular fluid. Human Reproduction. 2007; 22 (12): 3178–83.
- Expansion of liver cancer stem cells during aging in methionine adenosyltransferase 1A-deficient mice. Rountree CB, Senadheera S, Mato JM, et al. Hepatology. 2007; 47 (4): 1288–97.
- Akamine K, Mekaru K, Gibo K, et al. Impact of the one‐carbon metabolism on oocyte maturation, fertilization, embryo quality, and subsequent pregnancy. Reproductive Medicine and Biology. 2021; 20 (1): 76–82.
- Tatone C, Amicarelli F. The aging ovary — the poor granulosa cells. Fertility and Sterility. 2013; 99 (1): 12–17.
- Chappel S. The role of mitochondria from mature oocyte to viable blastocyst. Obstetrics and Gynecology International. 2013; 2013: 1–10.
- Youssef M. A. F. M., Abdelmoty HI, Elashmwi HA, et al. Oral antioxidants supplementation for women with unexplained infertility undergoing ICSI/IVF: Randomized controlled trial. Human Fertility. 2015; 18 (1): 38–42.
- Anchordoquy JP, Lizarraga RM, Anchordoquy JM, et al. Effect of cysteine, glutamate and glycine supplementation to in vitro fertilization medium during bovine early embryo development. Reproductive Biology. 2019; 19 (4): 349–55.