Funding: research project FURE-2022-0010.

Author contribution: Shepelkova GS — planning the experiments and experimental procedure, analysis of the results, manuscript writing; Chernyh NA — selection of patients for inclusion in the study, primary data analysis; Kosiakova VK — experimental procedure, primary data analysis; Sadovnikova SS — selection of patients for inclusion in the study; Ergeshov A — study design; Yeremeev VV — study design, analysis of the results, manuscript writing.

Compliance with ethical standards: the study was conducted as part of the research project FURE-2022-0010 of the Central Tuberculosis Research Institute and approved by the Ethics Committee of the Central Tuberculosis Research Institute (protocol No. 13/1 dated 28 December 2021). All the patients included in the study submitted the informed consent before enrollment.