2024 / 06

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DOI: 10.24075/brsmu.2024.069
Copyright: © 2024 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).

ORIGINAL RESEARCH

Assessment of the effect of hypothermia after simulated hypoxic ischemic encephalopathy based on blood metabolome

Eldarov CM1,2, Starodubtseva NL1, Shevtsova YuA1,2, Goryunov KV1, Ionov OV1, Silachev DN1,2
About authors

1 Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia

2 Belozersky Institute Of Physico-Chemical Biology, Moscow State University, Moscow, Russia

Correspondence should be addressed: Chupalav M. Eldarov
Akademika Oparina, 4, Moscow, 117997, Russia; ur.val4puhc@em

About paper

Funding: the study was supported by the Russian Federation on behalf of the Russian Science Foundation (grant No. 22-15-00454).

Author contribution: Eldarov CM — sample preparation, conducting HPLC-MS/MS, chromatography–mass spectrometry data processing, manuscript writing and editing; Starodubtseva NL — metabolomic data analysis, statistical analysis; manuscript writing and editing; Shevtsova YuA — conducting the model experiment, sample acquisition and characterization, discussing the results, manuscript writing and editing; Goryunov KV — conducting the model experiment, sample acquisition and characterization, manuscript writing and editing; Ionov OV — study planning, manuscript editing; Silachev DN — study planning, discussing the results, manuscript writing and editing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Belozersky Institute Of Physico-Chemical Biology, Moscow State University (protocol No. 8/22 dated 12 June 2022). The study was compliant with the standards of the Ethics Committee of the Belozersky Institute Of Physico- Chemical Biology, Moscow State University, and the Declaration of Helsinki (1964).

Received: 2024-12-03 Accepted: 2024-12-18 Published online: 2024-12-29
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