2024 / 06

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DOI: 10.24075/brsmu.2024.071
Copyright: © 2024 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).

ORIGINAL RESEARCH

Increased physical activity under conditions of normoxia causes idiopathic cachexia in Heterocephalus glaber

Adrianov MA1, Bobrov M2, Mamedov I3, Manskih V1, Rachkova AA1,4, Shelekhova AM1, Eldarov CM1,4, Averina OV1, Vyssokikh MYu1,4
About authors

1 Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia

2 Sirius University of Science and Technology, Sirius, Russia

3 Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia

4 Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia

Correspondence should be addressed: Mikhail A. Adrianov
Leninskie Gory, 1, bld. 40, 119992, Moscow, Russia; moc.liamg@hcstil.ay

About paper

Funding: the study was supported by the RSF grant No. 22-14-00160 "Comparative analysis of age signatures in long- and short-lived representatives of Heterocephalus glaber: caste-specificity of behavioral, biochemical and transcriptomic profiles".

Author contribution: Adrianov MA — manuscript authoring, conducting animal experiments; Bobrov M, Mamedov I — bioinformatics data analysis, microRNA sequencing; Manskih V — histologic assessment of tissues; Rachkova AA — manuscript authoring, bioinformatics data analysis, sample preparation and RNA extraction; Shelekhova AM, Averina OA — conducting animal experiments; Eldarov CM — bioinformatics data analysis; Vyssokikh MYu — experimental design, development of the concept, manuscript writing.

Compliance with ethical standards: the study was approved by the Ethics Committee of the Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University (protocol No. 2/20 dated 16 November 2022).

Received: 2024-12-11 Accepted: 2024-12-24 Published online: 2024-12-30
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