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ORIGINAL RESEARCH
Increased physical activity under conditions of normoxia causes idiopathic cachexia in Heterocephalus glaber
1 Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia
2 Sirius University of Science and Technology, Sirius, Russia
3 Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
4 Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia
Correspondence should be addressed: Mikhail A. Adrianov
Leninskie Gory, 1, bld. 40, 119992, Moscow, Russia; moc.liamg@hcstil.ay
Funding: the study was supported by the RSF grant No. 22-14-00160 "Comparative analysis of age signatures in long- and short-lived representatives of Heterocephalus glaber: caste-specificity of behavioral, biochemical and transcriptomic profiles".
Author contribution: Adrianov MA — manuscript authoring, conducting animal experiments; Bobrov M, Mamedov I — bioinformatics data analysis, microRNA sequencing; Manskih V — histologic assessment of tissues; Rachkova AA — manuscript authoring, bioinformatics data analysis, sample preparation and RNA extraction; Shelekhova AM, Averina OA — conducting animal experiments; Eldarov CM — bioinformatics data analysis; Vyssokikh MYu — experimental design, development of the concept, manuscript writing.
Compliance with ethical standards: the study was approved by the Ethics Committee of the Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University (protocol No. 2/20 dated 16 November 2022).