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ORIGINAL RESEARCH

Features of intrauterine microbiota in patients with endometrial polyps

Vanakova AI1,2, Dolgushina NV1,2, Denisov PA1, Goncharuk OD1, Muravieva VV1, Priputnevich TV1
About authors

1 Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia

2 Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia

Correspondence should be addressed: Angelina I. Vanakova
Trubetskaya, 8/2, Moscow, 119991, Russia; moc.liamg@avokanavanilegna

About paper

Author contribution: Dolgushina NV — study concept, design; Vanakova AI — data acquisition, manuscript writing; Goncharuk OD, Muravieva VV — laboratory testing; Denisov PA — statistical analysis, visualization; Muravieva VV, Priputnevich TV — data editing.

Received: 2025-01-21 Accepted: 2025-02-10 Published online: 2025-02-24
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Fig. 1. Cervical canal microbiota in patients with endometrial polyps (group 1) and the comparison group (group 2) (each cell represents bacterial content of the cervical canal in lg CFU/mL)
Fig. 2. Species richness and taxonomic diversity indices of intrauterine microbiota in patients of the studied groups
Fig. 3. Species diversity of intrauterine microbiota in patients of the studied groups: 1 — group with EPs, 2 — group without EPs
Table 1. Formulae for the species richness and diversity indices
Note: S — species richness (number of species); N — sample size (community size); ni — number of species i bacteria; с — number of species common for two communities; а — number of species in the first community; b — number of species in the second community.
Table 2. Clinical and medical history characteristics of patients
Note: * — Mе (Q25–Q75); * * * — Mе (min–max), Mann–Whitney U test; * * — abs (%), χ2 test; COCs — combined oral contraceptoves; GIT — gastrointestinal tract.
Table 3. Patient complaints
Note: abs (%),χ2 test.