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DOI: 10.24075/brsmu.2025.049
Copyright: © 2025 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).

ORIGINAL RESEARCH

Revival of radioimmunoassay for determination of insulin autoantibodies

Timofeev AV1 , Galimov RR1 , Kolesnikova EA1 , Artyuhov AS1 , Skoblov YuS2 , Taktarov SV3
About authors

1 Russian Children's Clinical Hospital (RCCH) — Pirogov Russian National Research Medical University, Moscow, Russia

2 Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia

3 Russian University of Medicine of the Ministry of Health of the Russian Federation, Moscow, Russia

Correspondence should be addressed: Alexei V. Timofeev
Leninsky prospect, 117, bld. 2, Moscow, 119571, Russia; moc.liamg@mitlavla

About paper

Author contribution: Timofeev AV — study concept, analysis of the results, manuscript editing; Galimov RR — selection and preparation of serum samples, RIA; Kolesnikova EA — manuscript writing; Artyuhov AS — statistical processing of the RIA results; Skoblov YuS — labeling of insulin with radioactive iodine, measuring the sample radioactivity with a gamma counter; Taktarov SV — preparation of serum samples, RIA.

Compliance with ethical standards: the study was conducted in accordance with the principles of the Declaration of Helsinki (1964) and further amendments.

Received: 2025-09-16 Accepted: 2025-10-16 Published online: 2025-10-26
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