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ORIGINAL RESEARCH

HMGB1 and anti-HMGB1 antibodies in systemic lupus erythematosus and other rheumatic diseases

Melamud MM1 , Ermakov EA1,2 , Tolmacheva AS1 , Sizikov AE1,3 , Klyaus NA4 , Nevinsky GA1 , Buneva VN1,2
About authors

1 Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia

2 Novosibirsk National Research State University, Novosibirsk, Russia

3 Research Institute of Fundamental and Clinical Immunology, Novosibirsk, Russia

4 Almazov National Medical Research Centre, Saint Petersburg, Russia

Correspondence should be addressed: Valentina N. Buneva
prospekt Akademika Lavrentieva, 8, Novosibirsk, 630090, Russia; ur.oib1@avenub

About paper

Funding: this work was supported by the Russian Science Foundation (Grant No. 23-15-00357).

Author contribution: Melamud MM — data analysis, manuscript writing; Ermakov EA — study design, manuscript writing and editing; Tolmacheva AS — experimental work, data analysis; Sizikov AE, Klyaus NA — material collection and preparation, data analysis; Nevinsky GA, Buneva VN — project supervision, editing. The contributions of Melamud MM and Ermakov EA were equal.

Compliance with ethical standards: The study was approved by the Ethics Committee of the Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (Protocol No. 3 dated June 19, 2023) and was conducted in accordance with the principles of the Declaration of Helsinki. All study participants provided written informed consent.

Received: 2025-10-29 Accepted: 2025-12-06 Published online: 2025-12-14
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